Willkommen bei der AG Pfirrmann

I studied Technical Biology from 1995 to 2002 at the University of Stuttgart, Germany, which spawned my keen and longterm interest in the ubiquitin proteasome system. I carried out my Masters (Diploma) work examining the Saccharomyces cerevisiae specific deubiquitinating enzyme Ubp6 in the laboratory of Rohan Baker at the John Curtin School of Medical Research, Canberra, Australia. In 2002, I returned to Stuttgart to join the laboratory of Dieter Wolf, where as a Ph.D. student I discovered a novel conserved E3 ubiquitin ligase complex and experimentally addressed certain aspects of the deubiquitinating enzyme Ubp14. In 2006, I moved to Stockholm, Sweden for postdoctoral studies, and first worked on the function of the Ubiquitin C-terminal hydrolase UCH-L1 in the laboratory of Maria Masucci at Karolinska Institute. In 2008, I joined the laboratory of Per O. Ljungdahl at Stockholm University, where I focused on the ubiquitin proteasome dependent activation mechanism of the chymotrypsin-like protease Ssy5.

Now we are interested in the function of a novel highly conserved putative ubiquitin ligase complex the Gid/CTLH complex.


Prof. Dr. Guido Posern

AG Ubiquitination: 
Leiter:    Thorsten Pfirrmann 
Telefon: (0345) 557-3802 
Fax:        (0345) 557-3804 
Email:     Email

Institut für Physiologische Chemie
Hollystrasse 1
06114 Halle (Saale)

Assistenz der Institutsleitung:
Ines Knipping
Telefon: (0345) 557-3812 
Fax:        (0345) 557-3811
Email:    Email